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David T Weaver Selected Research

PND 1186

1/2020Combinatorial Inhibition of Focal Adhesion Kinase and BCL-2 Enhances Antileukemia Activity of Venetoclax in Acute Myeloid Leukemia.
8/2017Inhibition of FAK kinase activity preferentially targets cancer stem cells.
1/2017The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma.
1/2016Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy.
5/2014Merlin deficiency predicts FAK inhibitor sensitivity: a synthetic lethal relationship.

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David T Weaver Research Topics

Disease

14Neoplasms (Cancer)
01/2020 - 12/2010
3Neoplasm Metastasis (Metastasis)
01/2020 - 01/2017
3Disease Progression
01/2020 - 01/2019
3Breast Neoplasms (Breast Cancer)
08/2017 - 01/2011
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2020 - 01/2017
2B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2020 - 10/2019
2Malignant Mesothelioma
01/2019 - 05/2014
2Triple Negative Breast Neoplasms
08/2017 - 12/2010
2Adenocarcinoma
01/2017 - 01/2016
2Squamous Cell Carcinoma of Head and Neck
01/2014 - 08/2011
2Hemorrhage
10/2005 - 02/2005
1Fatigue
01/2020
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2020
1Leukemia
01/2020
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
10/2019
1Marginal Zone B-Cell Lymphoma (MALT Lymphoma)
10/2019
1Non-Hodgkin Lymphoma (Lymphosarcoma)
10/2019
1Mesothelioma
01/2019
1Ovarian Neoplasms (Ovarian Cancer)
01/2019
1Hematologic Neoplasms (Hematological Malignancy)
12/2018
1Cough
12/2018
1Fever (Fevers)
12/2018
1Nausea
12/2018
1Neutropenia
12/2018
1Anemia
12/2018
1Diarrhea
12/2018
1Myeloid Leukemia (Leukemia, Myelocytic)
01/2017
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2016
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2016
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2015
1Neurofibromatosis 2 (Neurofibromatosis Type II)
05/2014
1Head and Neck Neoplasms (Head and Neck Cancer)
01/2014
1Pathologic Complete Response
05/2012
1Esophageal Neoplasms (Esophageal Cancer)
05/2012
1Thrombosis (Thrombus)
02/2005
1Genomic Instability
01/2004
1Ataxia Telangiectasia (Louis Bar Syndrome)
12/2002

Drug/Important Bio-Agent (IBA)

7Focal Adhesion Protein-Tyrosine KinasesIBA
01/2020 - 05/2014
6Biomarkers (Surrogate Marker)IBA
01/2014 - 12/2010
5PND 1186IBA
01/2020 - 05/2014
5Proteins (Proteins, Gene)FDA Link
01/2017 - 12/2010
3duvelisibIBA
01/2020 - 12/2018
3defactinibIBA
01/2020 - 08/2017
3PlatinumIBA
01/2019 - 08/2011
3Phosphotransferases (Kinase)IBA
08/2017 - 12/2002
3Formaldehyde (Formol)FDA Link
09/2012 - 01/2011
2ofatumumabFDA Link
01/2020 - 12/2018
2Neurofibromin 2 (Merlin)IBA
01/2019 - 05/2014
2Aldehyde DehydrogenaseIBA
01/2019 - 05/2014
2CateninsIBA
01/2019 - 07/2018
2ParaffinIBA
09/2012 - 05/2012
2DNA (Deoxyribonucleic Acid)IBA
08/2011 - 01/2004
1venetoclaxIBA
01/2020
1BilirubinIBA
01/2020
1Rituximab (Mabthera)FDA Link
10/2019
1Tyrosine (L-Tyrosine)FDA Link
01/2019
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
12/2018
1Deubiquitinating EnzymesIBA
07/2018
1130-nm albumin-bound paclitaxelIBA
01/2017
1Small Interfering RNA (siRNA)IBA
01/2017
1GemcitabineFDA Link
01/2017
1Collagen Type I (Type I Collagen)IBA
01/2017
1P-2 (P 2)IBA
01/2017
1VS-5584IBA
01/2015
1Paclitaxel (Taxol)FDA LinkGeneric
01/2015
1Cisplatin (Platino)FDA LinkGeneric
01/2015
1AsbestosIBA
05/2014
1MAP-kinase-activated kinase 2IBA
01/2014
1P 11 (P-11)IBA
09/2012
1A-Form DNA (A-DNA)IBA
09/2012
1AnthracyclinesIBA
09/2012
1Keratins (Keratin)IBA
09/2012
1Methotrexate (Mexate)FDA LinkGeneric
09/2012
1Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2011
1Pharmaceutical PreparationsIBA
01/2011
1Estrogen ReceptorsIBA
12/2010
1AntibodiesIBA
12/2010
1Progesterone Receptors (Progesterone Receptor)IBA
12/2010
1Warfarin (Coumadin)FDA LinkGeneric
02/2005
1CoagulantsIBA
02/2005
1Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
02/2005

Therapy/Procedure

9Drug Therapy (Chemotherapy)
10/2019 - 08/2011
7Therapeutics
10/2019 - 02/2005
1Radioimmunotherapy
10/2019
1Adjuvant Chemotherapy
01/2019
1Oral Administration
08/2017
1Immunotherapy
01/2016
1Induction Chemotherapy
01/2014
1Chemoradiotherapy
01/2014
1Palliative Care (Palliative Therapy)
09/2012
1Neoadjuvant Therapy
05/2012
1Radiotherapy
08/2011